Pneumonia Komunitas Pada Leukimia Prolimfositik
DOI:
https://doi.org/10.59188/jurnalsosains.v5i3.32098Keywords:
Community Acquired Pneumonia, Prolymphocytic Leukemia, Infeksi Paru, Imunosupresi, Leukemia Langka, Terapi Antibiotik, Manajemen KlinisAbstract
Community Acquired Pneumonia (CAP) merupakan salah satu penyebab utama morbiditas dan mortalitas, terutama pada pasien dengan kondisi imunokompromais seperti prolymphocytic leukemia. Penelitian ini mempresentasikan kasus seorang pria berusia 68 tahun yang didiagnosis CAP dengan komorbid leukemia prolimfositik. Data dikumpulkan melalui anamnesis, pemeriksaan fisik, dan penunjang (laboratorium dan radiologi). Diagnosis ditegakkan berdasarkan gejala klinis, hasil radiologi, dan penilaian risiko menggunakan Pneumonia Severity Index (PSI). Pasien mendapatkan terapi antibiotik empiris berupa levofloxacin dan ceftriaxone sesuai panduan terbaru. Studi ini menunjukkan bahwa CAP pada lansia dengan komorbiditas memerlukan pendekatan diagnostik dan terapi yang lebih komprehensif untuk mengurangi risiko komplikasi.
References
Perhimpunan Dokter Paru Indonesia (PDPI), 2022. Pneumonia Komunitas. Jakarta: Perhimpunan Dokter Paru Indonesia.
Tansarli, G.S. & Mylonakis, E., 2018. Systematic review and meta-analysis of the efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults. Antimicrobial Agents and Chemotherapy, 62(6), pp.e00635-18.
Gadsby, N.J. & Musher, D.M., 2022. The microbial etiology of community-acquired pneumonia in adults: from classical bacteriology to host transcriptional signatures. Clinical Microbiology Reviews, 35(4), pp.e0001522.
Wang, Z., Qiang, W., & Ke, H. 2020. A Handbook of 2019-nCoV Pneumonia Control and Prevention. Hubei Science and Technology Press, 1–108.
Rajeshbabu, Patturajan, Ayyanar, Muniappan, Rasool, Shaik Khaja, Sheriff, Mehboob Azrar, & Sekar, Thangavel. 2011. In vitro antibacterial activity of Piper betle L. and black betel CV. Kammar leaves against Staphylococcus aureus and Streptococcus pneumoniae. Journal of Pharmacy Research, 4(7), 2223–2225.
Yilmaz, Hatice Eylül BOZKURT. 2021. Factors Affecting Mortality In Geriatric Patients Diagnosed With Community-Acquired Pneumonia Treated In Intensive Care Units. Turk. Geriatr. Derg, 24, 212–219.
Watkins, R.R. & Lemonovich, T.L., 2011. Diagnosis and management of community-acquired pneumonia in adults. American Family Physician, 83(11), pp.1299–1306.
Chung, Kian Fan, Widdicombe, John G., & Boushey, Homer A. 2003. Cough: Causes, Mechanisms and Therapy.
Anderson, K. F., Lonsway, D. R., Rasheed, J. K., Biddle, J., Jensen, B., McDougal, L.K., Carey, R. B., Thompson, A., Stocker, S., & Limbago, B. 2007. Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae.Journal of Clinical Microbiology, 45(8), 2723–2725.
Muztika, Suci Alillah, Nasrul, Ellyza, & Alia, Eugeny. 2020. Prevalensi dan Pola Sensitivitas Antibiotik Klebsiella pneumoniae dan Escherichia coli Penghasil Extended Spectrum Beta Laktamase di RSUP Dr. M Djamil Padang. Jurnal Kesehatan Andalas, 9(2), 189–194.
Gutierrez, M., Bladek, P., Goksu, B., Murga-Zamalloa, C., Bixby, D. & Wilcox, R., 2023. T-cell prolymphocytic leukemia: diagnosis, pathogenesis, and treatment. International Journal of Molecular Sciences, 24(15), p.12106. Available at: https://doi.org/10.3390/ijms241512106
Metlay, J.P., Waterer, G.W., Long, A.C., Anzueto, A., Brozek, J., Crothers, K., Cooley, L.A., Dean, N.C., Fine, M.J. & Flanders, S.A., 2019. Diagnosis and treatment of adults with community-acquired pneumonia: an official clinical practice guideline of the American Thoracic Society and Infectious Diseases Society of America. American Journal of Respiratory and Critical Care Medicine, 200(7), pp.e45–e67.
Shah, Bashir Ahmed, Ahmed, Wasim, Dhobi, Ghulam Nabi, Shah, Naveed Nazir, Khursheed, Syed Quibtiya, & Haq, Inaamul. (n.d.). Validity of pneumonia severity index and CURB-65 severity scoring systems in community acquired pneumonia in an Indian setting. The Indian Journal of Chest Diseases & Allied Sciences, 52(1), 9–17.
Yadegarynia, D., Tehrani, S., Nejad Maghsoudi, F., Shojaeian, F., & Keyvanfar, A. 2022. Levofloxacin versus ceftriaxone and azithromycin for treating community-acquired pneumonia: a randomized clinical trial study. Iranian journal of microbiology, 14(4), 458–465.
Guz, D., Bracha, M., Steinberg, Y., Kozlovsky, D., Gafter-Gvili, A., & Avni, T. 2023. Ceftriaxone versus ampicillin for the treatment of community-acquired pneumonia. A propensity matched cohort study. Clinical Microbiology and Infection, 29(1), 70-76.
Khan, A.S., Iqbal, A., Muhammad, A.A., Mazhar, F., Lodhi, M.F., Ahmed, K.F., et al. 2023. Safety and Efficacy of Nemonoxacin vs Levofloxacin in Patients With Community-Acquired Pneumonia: A Systematic Review and Meta-Analysis of Randomized Control Trials. Cureus, 15(4), e37650. https://doi.org/10.7759/cureus.37650
Chen, J., Zhu, Y., Zheng, C., Zhao, W., & Liu, Q. 2023. Clinical efficacy of budesonide combined with acetylcysteine in the treatment of mycoplasma pneumonia infection. Immunity, Inflammation and Disease, 11(11), e1068. https://doi.org/10.1002/iid3.1068
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Karenina Shakeela, Eva Sri Diana, Vidhia Umami
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International (CC-BY-SA). that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
