Hubungan Antara Gambaran Head Computed Tomography Scan dan Elektroensefalogram Dengan Luaran Pada Pasien Post Stroke Seizure
DOI:
https://doi.org/10.59188/jurnalsosains.v5i5.32136Keywords:
Pemindaian Tomografi Komputer Kepala, Elektroensefalogram, Pasien Kejang Pasca StrokeAbstract
Seizure yang terjadi setelah stroke dan tidak memiliki riwayat epilepsi sebelumnya disebut sebagai post stroke seizure (PSS). Post stroke seizure dapat dibagi menjadi early seizure dan late seizure. Post stroke seizure meningkatkan mortalitas pada pasien, disabilitas pada saat keluar dari rumah sakit, dan juga perpanjangan masa rawat inap di rumah sakit. Pasien dengan post stroke seizure menunjukkan hasil fungsional yang buruk (mRS >2). Mengetahui hubungan antara gambaran head CT scan dan elektroensefalogram (EEG) dengan luaran pada pasien post stroke seizure di RS Adam Malik Medan. Penelitian ini bersifat analitik observasional dengan metode penelitian secara kohort prospektif dengan sumber data primer yang diperoleh secara konsekutif dari semua pasien PSS yang dirawat inap di RS Adam Malik Medan dan telah dilakukan pemeriksaan head CT scan dan EEG. Luaran pasien PSS dinilai dengan skor mRS pada hari ke-14 sejak seizure. Terdapat 24 subjek penelitian yang memenuhi kriteria inklusi dan eksklusi yang berusia antara 18-74 tahun dan terdiri dari 18 subjek laki-laki dan 6 subjek perempuan. Terdapat hubungan antara gambaran head CT Scan dengan luaran klinis pasien post stroke seizure berdasarkan hasil uji chi square yang dilakukan dengan nilai p = 0,041(<0,05) untuk lokasi lesi dan p = 0,018 (<0,05) untuk luas lesi. Terdapat hubungan antara EEG dengan luaran klinis pasien post stroke seizure berdasarkan hasil uji Chi Square yang dilakukan didapati nilai p = 0,001 (<0,05). Terdapat hubungan bermakna antara gambaran Head CT Scan dan EEG terhadap luaran pada pasien.
References
Agarwal, A., Sharma, J., Srivastava, M. V, Bhatia, R., Singh, M. B., & Gupta, A. (2021). Early Post‐Stroke Seizures in Acute Ischemic Stroke: A Prospective Cohort Study. Annals of Indian Academy of Neurology, 24(4), 580–585. https://doi.org/10.4103/aian.AIAN_138_21
Alsaad, F., Alkeneetir, N., Almatroudi, M., Alatawi, A., Alotaibi, A., Aldibasi, O., & Khatri, I. A. (2022). Early seizures in stroke – frequency, risk factors, and effect on patient outcomes in a tertiary center in Saudi Arabia. Neurosciences, 27(2).
Bentes, C., Peralta, A. R., Martins, H., Casimiro, C., Morgado, C., Franco, A. C., & Viana, P. (2017). Seizures, electroencephalographic abnormalities, and outcome of ischemic stroke patients. Epilepsia Open, 2(4), 441–452. https://doi.org/10.1002/epi4.12071
Cheng, B., Forkert, N. D., Zavaglia, M., Hilgetag, C. C., Golsari, A., & Siemonsen, S. (2014). Influence of Stroke Infarct Location on Functional Outcome Measured by the Modified Rankin Scale. Stroke, 45(6), 1695–1702. https://doi.org/10.1161/STROKEAHA.114.005599
Chilamkurthy, S., Ghosh, R., Tanamala, S., Biviji, M., Campeau, N. G., Venugopal, V. K., Mahajan, V., Rao, P., & Warier, P. (2018). Deep learning algorithms for detection of critical findings in head CT scans: a retrospective study. The Lancet, 392(10162). https://doi.org/10.1016/S0140-6736(18)31645-3
Ernst, M., Boers, A. M. M., Forkert, N. D., Berkhemer, O. A., Roos, Y. B., & Dippel, D. W. J. (2018). Impact of Ischemic Lesion Location on the mRS Score in Patients with Ischemic Stroke: A Voxel-Based Approach. American Journal of Neuroradiology, 39(11), 1989–1994. https://doi.org/10.3174/ajnr.A5819
Fu, Y., Feng, L., & Xiao, B. (2021). Current advances on mechanisms and treatment of post-stroke seizures. In Acta Epileptologica (Vol. 3, Issue 1). https://doi.org/10.1186/s42494-021-00047-z
Galovic, M., Ferreira-Atuesta, C., Abraira, L., Dohler, N., Sinka, L., Brigo, F., & Bentes, C. (2021). Seizures and Epilepsy After Stroke: Epidemiology, Biomarkers and Management. Drugs & Aging, 38(4), 285–299. https://doi.org/10.1007/s40266-021-00831-8
Heiss, W. D., & Kidwell, C. S. (2015). Imaging for Prediction of Functional Outcome and Assessment of Recovery in Ischemic Stroke. Stroke, 46(5), 1195–1201. https://doi.org/10.1161/STROKEAHA.114.007026
Lidetu, T., & Zewdu, D. (2023). Incidence and predictors of post stroke seizure among adult stroke patients admitted at Felege Hiwot comprehensive specialized hospital, Bahir Dar, North West Ethiopia, 2021: A retrospective follow up study. BMC Neurology, 23, 2–7. https://doi.org/10.1186/s12883-023-03127-4
Nandan, A., Zhouu, Y. M., Demoe, A. W., Jain, P., & Widjaja, E. (2023). Incidence and risk factors of post-stroke seizures and epilepsy: Systematic review and meta-analysis. Journal of International Medical Research. https://doi.org/10.1177/03000605231173956
Ospel, J. M., Hill, M. D., Menon, B. K., Demchuk, A., McTaggart, R., Nogueira, R., & Poppe, A. (2021). Strength of Association between Infarct Volume and Clinical Outcome Depends on the Magnitude of Infarct Size: Results from the ESCAPE-NA1 Trial. American Journal of Neuroradiology, 42(6), 1041–1046. https://doi.org/10.3174/ajnr.A7032
Pande, S. D., Lwin, M. T., Kyaw, K. M., Khine, A. A., Thant, A. A., Win, M. M., & Morris, J. (2018). Post-stroke seizure—Do the locations, types and managements of stroke matter? Epilepsia Open, 3(3). https://doi.org/10.1002/epi4.12249
Rizky, I., Putu, N., Jeniyanthi, R., Istri, C., Widiastuti, A., Radiodiagnostik, A. T., Radioterapi, D., & Penulis, I. K. (2024). Prosedur Pemeriksaan CT Scan Kepala Dengan Klinis Stroke Hemorrhagic Di RS Bhayangkara Makassar. Journal of Educational Innovation and Public Health, 2(1).
Tomari, S., Tanaka, T., Ihara, M., Matsuki, T., Fukuma, K., Matsubara, S., Nagatsuka, K., & Toyoda, K. (2017). Risk factors for post-stroke seizure recurrence after the first episode. Seizure, 52. https://doi.org/10.1016/j.seizure.2017.09.007
Wang, G., Jia, H., Chen, C., Lang, S., Liu, X., & Xia, C. (2013). Analysis of Risk Factors for First Seizure after Stroke in Chinese Patients. BioMed Research International, 2013. https://doi.org/10.1155/2013/702871
Xu, M. Y. (2019). Poststroke seizure: Optimising its management. Stroke and Vascular Neurology, 4. https://doi.org/10.1136/svn-2019-000175
Zelano, J., Holtkamp, M., Agarwal, N., Lattanzi, S., Trinka, E., & Brigo, F. (2020). How to diagnose and treat post-stroke seizures and epilepsy. Epileptic Disorders, 22(3). https://doi.org/10.1684/epd.2020.1159
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